Thursday August 28, 2008
SRMD and PUD

We commonly use terms Stress ulcer (Stress Related Mucosal Disease = SRMD) and Peptic ulcer disease (PUD) interchangeably in ICU while talking "GI prophylaxis". But both are 2 different conditions. Probably what we are worried in our "unit" patients is mostly SRMD.

SRMD is multiple superficial erosions occurring in proximal gastric bulb involving superficial capillaries secondary to mucosal hypoperfusion and perforations are rare.

PUD is few deep erosions occurring usually in duodenum involving one vessel secondary to other reasons (drugs, H.Pylori, hypersecretory states etc.) and perforation is common.